| Gene Information | |
|---|---|
| Gene Name | IMPA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 288 |
| Protein Names | Inositol monophosphatase 2 (IMP 2) (IMPase 2) (EC 3.1.3.25) (Inositol-1(or 4)-monophosphatase 2) (Myo-inositol monophosphatase A2) |
| Target Name | inositol-1(or4)-monophosphatase |
| Target Type | Literature-reported target |
| Gene Age | 454 ( ENSG00000141401 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O14732 |
| Gene Card | IMPA2 |
| Uniprot ID | O14732 |
| Pfam | PF00459 |
| In ASD | no |
| Allosteric Prediction | yes (0.32094167) |
| Ortholog in Animals | Alpaca_ IMPA2 ( ortholog_one2one ) Dog_ IMPA2 ( ortholog_one2one ) GuineaPig_ IMPA2 ( ortholog_one2one ) Macaque_ IMPA2 ( ortholog_one2one ) Mouse_ Impa2 ( ortholog_one2one ) Pig_ IMPA2 ( ortholog_one2one ) Rat_ Impa2 ( ortholog_one2one ) |
| Ohnologs | IMPA1 |
| Paralogs | BPNT1, IMPA1, INPP1, BPNT2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CZH (X-ray 2.70A ) 2CZI (X-ray 3.00A ) 2CZK (X-ray 2.90A ) 2DDK (X-ray 2.70A ) 2FVZ (X-ray 2.40A ) |
| DBSNP | rs16976948 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17068342}. |
| Mouse PG classification | NA |
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