| Gene Information | |
|---|---|
| Gene Name | IMPA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 277 |
| Protein Names | Inositol monophosphatase 1 (IMP 1) (IMPase 1) (EC 3.1.3.25) (D-galactose 1-phosphate phosphatase) (EC 3.1.3.94) (Inositol-1(or 4)-monophosphatase 1) (Lithium-sensitive myo-inositol monophosphatase A1) |
| Target Name | inositol monophosphatase 1 |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000133731 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P29218 |
| Gene Card | IMPA1 |
| Uniprot ID | P29218 |
| Pfam | PF00459 |
| In ASD | no |
| Allosteric Prediction | yes (0.515986416) |
| Ortholog in Animals | Alpaca_ IMPA1 ( ortholog_one2one ) Dog_ IMPA1 ( ortholog_one2one ) GuineaPig_ IMPA1 ( ortholog_one2one ) Macaque_ IMPA1 ( ortholog_one2one ) Mouse_ Impa1 ( ortholog_one2one ) Pig_ IMPA1 ( ortholog_one2one ) Rat_ Impa1 ( ortholog_one2one ) Rabbit_ IMPA1 ( ortholog_one2one ) |
| Ohnologs | IMPA2 |
| Paralogs | BPNT1, INPP1, BPNT2, IMPA2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1AWB (X-ray 2.50A ) 1IMA (X-ray 2.30A ) 1IMB (X-ray 2.20A ) 1IMC (X-ray 2.60A ) 1IMD (X-ray 2.60A ) 1IME (X-ray 2.25A ) 1IMF (X-ray 2.50A ) 2HHM (X-ray 2.10A ) 4AS4 (X-ray 1.70A ) 6GIU (X-ray 1.39A ) 6GJ0 (X-ray 1.73A ) 6ZK0 (X-ray 1.47A ) 7VCE (X-ray 2.60A ) |
| DBSNP | rs204781 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17068342}. |
| Mouse PG classification | NA |
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