| Gene Information | |
|---|---|
| Gene Name | RBP5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 135 |
| Protein Names | Retinol-binding protein 5 (Cellular retinol-binding protein III) (CRBP-III) (HRBPiso) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000139194 ) 3 ( ENSG00000288369 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P82980 |
| Gene Card | RBP5 |
| Uniprot ID | P82980 |
| Pfam | PF00061 |
| In ASD | no |
| Allosteric Prediction | no (-1.08116662) |
| Ortholog in Animals | Alpaca_ RBP5 ( ortholog_one2one ) GuineaPig_ RBP5 ( ortholog_one2one ) Pig_ RBP5 ( ortholog_one2one ) Rabbit_ RBP5 ( ortholog_one2one ) |
| Ohnologs | RBP2, RBP1, RBP7 |
| Paralogs | CRABP1, FABP9, FABP5, FABP12, RBP1, FABP4, PMP2, RBP2, RBP7, FABP3, FABP2, FABP6, FABP7, FABP1, CRABP2 |
| Tissue | NA |
| Tissue Specificity | Higher expression in adult kidney and liver and to a lesser extent in adult and fetal spleen, adult lymph nodes and appendix, and fetal liver and kidney. Strongly decreased in hepatocellular carcinoma tissues (at protein level). {ECO:0000269|PubMed:11274389, ECO:0000269|PubMed:17497168}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 1GGL (X-ray 2.31A ) 6E5W (X-ray 2.50A ) |
| DBSNP | rs10963 rs7969705 rs2290237 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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