| Gene Information | |
|---|---|
| Gene Name | ILKAP |
| Organism | Homo sapiens (Human) |
| Gene Length | 392 |
| Protein Names | Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) (EC 3.1.3.16) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000132323 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H0C8 |
| Gene Card | ILKAP |
| Uniprot ID | Q9H0C8 |
| Pfam | PF00481 |
| In ASD | no |
| Allosteric Prediction | no (-0.528574445) |
| Ortholog in Animals | Alpaca_ ILKAP ( ortholog_one2one ) Dog_ ILKAP ( ortholog_one2one ) GuineaPig_ ILKAP ( ortholog_one2one ) Macaque_ ILKAP ( ortholog_one2one ) Mouse_ Ilkap ( ortholog_one2one ) Pig_ ILKAP ( ortholog_one2one ) Rat_ Ilkap ( ortholog_one2one ) Rabbit_ ILKAP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PDP2, TAB1, PPM1B, PPM1L, PPM1N, PP2D1, PDP1, PPM1A, PPM1D, PPM1E, PPM1G, PPM1H, PPM1J, PPM1M, PPM1F, PPM1K |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Highest levels expressed in striated muscle. Much lower levels evident in various smooth muscle tissues. {ECO:0000269|PubMed:11331582}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34371548 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11331582}. |
| Mouse PG classification | NA |
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