| Gene Information | |
|---|---|
| Gene Name | GNAT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 354 |
| Protein Names | Guanine nucleotide-binding protein G(t) subunit alpha-3 (Gustducin alpha-3 chain) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000214415 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | A8MTJ3 |
| Gene Card | GNAT3 |
| Uniprot ID | A8MTJ3 |
| Pfam | PF00503 |
| In ASD | no |
| Allosteric Prediction | yes (0.79349579) |
| Ortholog in Animals | Alpaca_ GNAT3 ( ortholog_one2one ) Dog_ GNAT3 ( ortholog_one2one ) GuineaPig_ GNAT3 ( ortholog_one2one ) Macaque_ GNAT3 ( ortholog_one2one ) Mouse_ Gnat3 ( ortholog_one2one ) Pig_ GNAT3 ( ortholog_one2one ) Rat_ Gnat3 ( ortholog_one2one ) Rabbit_ GNAT3 ( ortholog_one2one ) |
| Ohnologs | GNAT1 |
| Paralogs | GNAZ, GNAT1, GNAL, GNA13, GNA12, GNAI2, GNAT2, GNAO1, GNAI3, GNAI1, GNA15, GNA11, GNAS, GNA14, GNAQ |
| Tissue | NA |
| Tissue Specificity | Expressed in taste buds (sensory organs of clustered epithelial cells) of the circumvallate and foliate papillae of the tongue at protein level. Expressed in enteroendocrine L cells of the gut. Detected also in spermatozoa. {ECO:0000269|PubMed:16728727, ECO:0000269|PubMed:17021831, ECO:0000269|PubMed:17724332, ECO:0000269|PubMed:8015379}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);0.083333(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:8015379}. Note=Dual distribution pattern; plasmalemmal pattern with apical region localization and cytosolic pattern with localization throughout the cytoplasm. |
| Mouse PG classification | NA |
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