| Gene Information | |
|---|---|
| Gene Name | MSRA |
| Organism | Homo sapiens (Human) |
| Gene Length | 235 |
| Protein Names | Mitochondrial peptide methionine sulfoxide reductase (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase) (Protein-methionine-S-oxide reductase) (PMSR) |
| Target Name | mitochondrial peptide methionine sulfoxide reductase |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000175806 ) 3 ( ENSG00000285250 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9UJ68 |
| Gene Card | MSRA |
| Uniprot ID | Q9UJ68 |
| Pfam | PF01625 |
| In ASD | no |
| Allosteric Prediction | no (-0.330987377) |
| Ortholog in Animals | Alpaca_ MSRA ( ortholog_one2one ) Dog_ MSRA ( ortholog_one2one ) GuineaPig_ MSRA ( ortholog_one2one ) Mouse_ Msra ( ortholog_one2one ) Pig_ MSRA ( ortholog_one2one ) Rat_ Msra ( ortholog_one2one ) Rabbit_ MSRA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MSRB1, MSRB2, MSRB3 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highest expression in adult kidney and cerebellum, followed by liver, heart ventricles, bone marrow and hippocampus. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Mitochondrion.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm. Nucleus.; [Isoform 5]: Cytoplasm. Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. |
| Mouse PG classification | NA |
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