| Gene Information | |
|---|---|
| Gene Name | IL4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 153 |
| Protein Names | Interleukin-4 (IL-4) (B-cell stimulatory factor 1) (BSF-1) (Binetrakin) (Lymphocyte stimulatory factor 1) (Pitrakinra) |
| Target Name | interleukin-4 |
| Target Type | Clinical trial target |
| Gene Age | 424 ( ENSG00000113520 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P05112 |
| Gene Card | IL4 |
| Uniprot ID | P05112 |
| Pfam | PF00727 |
| In ASD | no |
| Allosteric Prediction | yes (0.658189745) |
| Ortholog in Animals | Alpaca_ IL4 ( ortholog_one2many ) Dog_ IL4 ( ortholog_one2one ) Macaque_ IL4 ( ortholog_one2one ) Mouse_ Il4 ( ortholog_one2one ) Pig_ IL4 ( ortholog_one2one ) Rat_ Il4 ( ortholog_one2one ) Rabbit_ IL-4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005990(Rat);0.060000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1BBN (NMR - ) 1BCN (NMR - ) 1CYL (NMR - ) 1HIJ (X-ray 3.00A ) 1HIK (X-ray 2.60A ) 1HZI (X-ray 2.05A ) 1IAR (X-ray 2.30A ) 1ITI (NMR - ) 1ITL (NMR - ) 1ITM (NMR - ) 1RCB (X-ray 2.25A ) 2B8U (X-ray 1.80A ) 2B8X (X-ray 1.70A ) 2B8Y (X-ray 1.80A ) 2B8Z (X-ray 2.50A ) 2B90 (X-ray 2.10A ) 2B91 (X-ray 2.00A ) 2CYK (NMR - ) 2D48 (X-ray 1.65A ) 2INT (X-ray 2.35A ) 3BPL (X-ray 2.93A ) 3BPN (X-ray 3.02A ) 3QB7 (X-ray 3.24A ) 4YDY (X-ray 2.00A ) 5FHX (X-ray 2.55A ) 6OEL (X-ray 3.10A ) |
| DBSNP | rs4986964 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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