| Gene Information | |
|---|---|
| Gene Name | IL2RA |
| Organism | Homo sapiens (Human) |
| Gene Length | 272 |
| Protein Names | Interleukin-2 receptor subunit alpha (IL-2 receptor subunit alpha) (IL-2-RA) (IL-2R subunit alpha) (IL2-RA) (TAC antigen) (p55) (CD antigen CD25) |
| Target Name | interleukin 2 receptor alpha |
| Target Type | Successful target |
| Gene Age | 424 ( ENSG00000134460 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P01589 |
| Gene Card | IL2RA |
| Uniprot ID | P01589 |
| Pfam | PF00084 |
| In ASD | no |
| Allosteric Prediction | yes (0.660729562) |
| Ortholog in Animals | Alpaca_ IL2RA ( ortholog_one2one ) Dog_ IL2RA ( ortholog_one2one ) GuineaPig_ IL2RA ( ortholog_one2one ) Macaque_ IL2RA ( ortholog_one2one ) Mouse_ Il2ra ( ortholog_one2one ) Pig_ IL2RA ( ortholog_one2one ) Rat_ Il2ra ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | appendix, lymph.node, tonsil, spleen |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1Z92 (X-ray 2.80A ) 2B5I (X-ray 2.30A ) 2ERJ (X-ray 3.00A ) 3IU3 (X-ray 2.90A ) 3NFP (X-ray 2.86A ) 6VWU (X-ray 3.40A ) 6YIO (X-ray 1.83A ) 7F9W (EM 3.20A ) |
| DBSNP | rs796051888 rs796051887 rs12722712 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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