| Gene Information | |
|---|---|
| Gene Name | IL27 |
| Organism | Homo sapiens (Human) |
| Gene Length | 243 |
| Protein Names | Interleukin-27 subunit alpha (IL-27 subunit alpha) (IL-27-A) (IL27-A) (Interleukin-30) (p28) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000197272 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q8NEV9 |
| Gene Card | IL27 |
| Uniprot ID | Q8NEV9 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.093918098) |
| Ortholog in Animals | Alpaca_ IL27 ( ortholog_one2one ) Dog_ IL27 ( ortholog_one2one ) GuineaPig_ IL27 ( ortholog_one2one ) Macaque_ IL27 ( ortholog_one2one ) Mouse_ Il27 ( ortholog_one2one ) Pig_ IL27 ( ortholog_one2one ) Rat_ Il27 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in monocytes and in placenta. {ECO:0000269|PubMed:12121660}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7U7N (EM 3.47A ) |
| DBSNP | rs17855750 rs181206 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:12121660}. Note=Does not seem to be secreted without coexpression of EBI3. |
| Mouse PG classification | NA |
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