Gene Information
Gene NameIL25
OrganismHomo sapiens (Human)
Gene Length177
Protein NamesInterleukin-25 (IL-25) (Interleukin-17E) (IL-17E)
Target Nameinterleukin-25
Target TypeClinical trial target
Gene Age680 ( ENSG00000166090 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9H293
Gene CardIL25
Uniprot IDQ9H293
PfamPF06083
In ASDno
Allosteric Predictionno (-0.852705091)
Ortholog in AnimalsAlpaca_ IL25 ( ortholog_one2one )
GuineaPig_ IL25 ( ortholog_one2one )
Macaque_ IL25 ( ortholog_one2one )
Mouse_ Il25 ( ortholog_one2one )
Pig_ IL25 ( ortholog_one2one )
Rat_ Il25 ( ortholog_one2one )
Rabbit_ IL25 ( ortholog_one2one )
OhnologsNA
ParalogsIL17F, IL17D, IL17B, IL17A, IL17C
TissueNA
Tissue SpecificityExpressed at low levels in several tissues, including brain, kidney, lung, prostate, testis, spinal cord, adrenal gland, and trachea.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7UWJ  (EM  3.20A  7UWK  (EM  4.40A  7UWL  (EM  3.70A 
DBSNP NA 
Subcellular location [CC]Secreted.
Mouse PG classificationNA
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