| Gene Information | |
|---|---|
| Gene Name | IL21 |
| Organism | Homo sapiens (Human) |
| Gene Length | 162 |
| Protein Names | Interleukin-21 (IL-21) (Za11) |
| Target Name | interleukin-21 |
| Target Type | Clinical trial target |
| Gene Age | 680 ( ENSG00000138684 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9HBE4 |
| Gene Card | IL21 |
| Uniprot ID | Q9HBE4 |
| Pfam | PF02372 |
| In ASD | no |
| Allosteric Prediction | no (-0.026794821) |
| Ortholog in Animals | Alpaca_ IL21 ( ortholog_one2one ) Dog_ IL21 ( ortholog_one2one ) GuineaPig_ IL21 ( ortholog_one2one ) Macaque_ IL21 ( ortholog_one2one ) Mouse_ Il21 ( ortholog_one2one ) Pig_ IL21 ( ortholog_one2one ) Rat_ Il21 ( ortholog_one2one ) Rabbit_ IL21 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. {ECO:0000269|PubMed:11081504}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2OQP (NMR - ) 3TGX (X-ray 2.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:11081504}. |
| Mouse PG classification | LPG |
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