Gene Information
Gene NameIL20RB
OrganismHomo sapiens (Human)
Gene Length311
Protein NamesInterleukin-20 receptor subunit beta (IL-20 receptor subunit beta) (IL-20R-beta) (IL-20RB) (Fibronectin type III domain containing 6) (FNDC6) (IL-20R2)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000174564 )
Evolutionary StageVertebrata
AlphaFoldDBQ6UXL0
Gene CardIL20RB
Uniprot IDQ6UXL0
PfamPF09294; PF01108
In ASDno
Allosteric Predictionno (-0.417599792)
Ortholog in AnimalsAlpaca_ IL20RB ( ortholog_one2one )
Dog_ IL20RB ( ortholog_one2one )
GuineaPig_ IL20RB ( ortholog_one2one )
Macaque_ IL20RB ( ortholog_one2one )
Mouse_ Il20rb ( ortholog_one2one )
Pig_ IL20RB ( ortholog_one2one )
Rat_ Il20rb ( ortholog_one2one )
Rabbit_ IL20RB ( ortholog_one2one )
OhnologsNA
ParalogsIFNAR1, IL22RA2, IFNGR2, IL22RA1, F3, IFNLR1, IL10RA, IL20RA, IFNAR2, IFNGR1, IL10RB
Tissueskin, zone.of.skin, esophagus.mucosa, lower.leg.skin, suprapubic.skin
Tissue SpecificityWidely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin. {ECO:0000269|PubMed:11163236}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4DOH  (X-ray  2.80A  6DF3  (X-ray  2.15A 
DBSNP NA 
Subcellular location [CC]Membrane {ECO:0000250};
Single-pass type I membrane protein {ECO:0000250}.
Mouse PG classificationNA
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