| Gene Information | |
|---|---|
| Gene Name | IL20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 176 |
| Protein Names | Interleukin-20 (IL-20) (Cytokine Zcyto10) |
| Target Name | interleukin-20 |
| Target Type | Clinical trial target |
| Gene Age | 544 ( ENSG00000162891 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NYY1 |
| Gene Card | IL20 |
| Uniprot ID | Q9NYY1 |
| Pfam | PF00726 |
| In ASD | no |
| Allosteric Prediction | no (-0.402420673) |
| Ortholog in Animals | Alpaca_ IL20 ( ortholog_one2one ) Dog_ IL20 ( ortholog_one2one ) GuineaPig_ IL20 ( ortholog_one2one ) Macaque_ IL20 ( ortholog_one2one ) Mouse_ Il20 ( ortholog_one2one ) Pig_ IL20 ( ortholog_one2one ) Rat_ Il20 ( ortholog_one2one ) Rabbit_ IL20 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IL19, IL24, IL10, IL26 |
| Tissue | NA |
| Tissue Specificity | Expressed in most tissues and five major cell types: epithelial cells (primarily skin, buccal mucosa, tongue, nasal mucosa, lung, ureter, breast, prostate, fallopian tube, and adrenal gland), myoepithelial cells (mainly prostate), endothelial cells (mainly in small vessels or capillaries), macrophages, and skeletal muscle. Isoform 2 was detected in the lung tissue only. {ECO:0000269|PubMed:16908179}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 4DOH (X-ray 2.80A ) |
| DBSNP | rs35856950 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:34403503}. |
| Mouse PG classification | NA |
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