| Gene Information | |
|---|---|
| Gene Name | IL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 153 |
| Protein Names | Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin) |
| Target Name | interleukin-2 |
| Target Type | Successful target |
| Gene Age | 680 ( ENSG00000109471 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P60568 |
| Gene Card | IL2 |
| Uniprot ID | P60568 |
| Pfam | PF00715 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000192696) |
| Ortholog in Animals | Alpaca_ IL2 ( ortholog_one2one ) Dog_ IL2 ( ortholog_one2one ) GuineaPig_ IL2 ( ortholog_one2one ) Macaque_ IL2 ( ortholog_one2one ) Mouse_ Il2 ( ortholog_one2one ) Pig_ IL2 ( ortholog_one2one ) Rat_ Il2 ( ortholog_one2one ) Rabbit_ IL-2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1IRL (NMR - ) 1M47 (X-ray 1.99A ) 1M48 (X-ray 1.95A ) 1M49 (X-ray 2.00A ) 1M4A (X-ray 2.18A ) 1M4B (X-ray 2.15A ) 1M4C (X-ray 2.40A ) 1NBP (X-ray 2.20A ) 1PW6 (X-ray 2.60A ) 1PY2 (X-ray 2.80A ) 1QVN (X-ray 2.70A ) 1Z92 (X-ray 2.80A ) 2B5I (X-ray 2.30A ) 2ERJ (X-ray 3.00A ) 3INK (X-ray 2.50A ) 3QAZ (X-ray 3.80A ) 3QB1 (X-ray 3.10A ) 4NEJ (X-ray 1.92A ) 4NEM (X-ray 1.93A ) 5LQB (X-ray 1.95A ) 5M5E (X-ray 2.30A ) 5UTZ (X-ray 2.75A ) 6LX3 (EM 3.15A ) 6LXW (EM 3.27A ) 6VWU (X-ray 3.40A ) 6YE3 (X-ray 2.89A ) 7DR4 (X-ray 2.49A ) 7M2G (X-ray 1.79A ) 7RA9 (X-ray 2.20A ) 7RAA (X-ray 2.69A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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