| Gene Information | |
|---|---|
| Gene Name | IL1RA |
| Organism | Homo sapiens (Human) |
| Gene Length | 177 |
| Protein Names | Interleukin-1 receptor antagonist protein (IL-1RN) (IL-1ra) (IRAP) (ICIL-1RA) (IL1 inhibitor) (Anakinra) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P18510 |
| Gene Card | IL1RN |
| Uniprot ID | P18510 |
| Pfam | PF00340 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | The intracellular form of IL1RN is predominantly expressed in epithelial cells. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1ILR (X-ray 2.10A ) 1ILT (X-ray 2.00A ) 1IRA (X-ray 2.70A ) 1IRP (NMR - ) 2IRT (X-ray 3.20A ) |
| DBSNP | rs45507693 |
| Subcellular location [CC] | [Isoform 1]: Secreted {ECO:0000269|PubMed:32384874}.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm. |
| Mouse PG classification | NA |
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