| Gene Information | |
|---|---|
| Gene Name | UPK3A |
| Organism | Homo sapiens (Human) |
| Gene Length | 287 |
| Protein Names | Uroplakin-3a (UP3a) (Uroplakin III) (UPIII) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000100373 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O75631 |
| Gene Card | UPK3A |
| Uniprot ID | O75631 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.057659083) |
| Ortholog in Animals | Alpaca_ UPK3A ( ortholog_one2one ) Dog_ UPK3A ( ortholog_one2one ) GuineaPig_ UPK3A ( ortholog_one2one ) Macaque_ UPK3A ( ortholog_one2one ) Mouse_ Upk3a ( ortholog_one2one ) Pig_ UPK3A ( ortholog_one2one ) Rat_ Upk3a ( ortholog_one2one ) Rabbit_ UPK3A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | UPK3B, UPK3BL2, UPK3BL1 |
| Tissue | prostate, urinary.bladder, artery, penis, smooth.muscle, submandibular.gland |
| Tissue Specificity | Expressed in ureter. {ECO:0000269|PubMed:9846985}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.2(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6006979 rs1057353 rs121918187 rs121918186 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER). {ECO:0000250}. |
| Mouse PG classification | NA |
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