| Gene Information | |
|---|---|
| Gene Name | IL18BP |
| Organism | Homo sapiens (Human) |
| Gene Length | 194 |
| Protein Names | Interleukin-18-binding protein (IL-18BP) (Tadekinig-alfa) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000137496 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O95998 |
| Gene Card | IL18BP |
| Uniprot ID | O95998 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.591748588) |
| Ortholog in Animals | Alpaca_ IL18BP ( ortholog_one2one ) GuineaPig_ IL18BP ( ortholog_one2one ) Macaque_ IL18BP ( ortholog_one2one ) Mouse_ Il18bp ( ortholog_one2one ) Rat_ Il18bp ( ortholog_one2one ) Rabbit_ IL18BP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in heart, lung, placenta and spleen. {ECO:0000269|PubMed:10023777, ECO:0000269|PubMed:10094485}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7AL7 (X-ray 1.80A ) |
| DBSNP | rs5743672 rs5743673 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:31213488}. |
| Mouse PG classification | NA |
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