| Gene Information | |
|---|---|
| Gene Name | IL17RE |
| Organism | Homo sapiens (Human) |
| Gene Length | 667 |
| Protein Names | Interleukin-17 receptor E (IL-17 receptor E) (IL-17RE) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000163701 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8NFR9 |
| Gene Card | IL17RE |
| Uniprot ID | Q8NFR9 |
| Pfam | PF15037; PF08357 |
| In ASD | no |
| Allosteric Prediction | no (-1.195215168) |
| Ortholog in Animals | Alpaca_ IL17RE ( ortholog_one2one ) Dog_ IL17RE ( ortholog_one2one ) Macaque_ IL17RE ( ortholog_one2one ) Mouse_ Il17re ( ortholog_one2one ) Rat_ Il17re ( ortholog_one2one ) Rabbit_ IL17RE ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IL17RB, IL17RA, IL17RD, IL17RC |
| Tissue | small.intestine |
| Tissue Specificity | Predominantly expressed in mucosal tissues with high levels in keratinocytes and colon epithelial cells. Very low expression in dermal fibroblasts. Expressed in various tumor cell lines. {ECO:0000269|PubMed:16310341, ECO:0000269|PubMed:21993848}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7356031 rs9870003 rs7647642 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.; [Isoform 2]: Cytoplasm {ECO:0000305}.; [Isoform 3]: Secreted {ECO:0000305}.; [Isoform 4]: Cytoplasm {ECO:0000305}.; [Isoform 5]: Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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