| Gene Information | |
|---|---|
| Gene Name | TRERF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1200 |
| Protein Names | Transcriptional-regulating factor 1 (Breast cancer anti-estrogen resistance 2) (Transcriptional-regulating protein 132) (Zinc finger protein rapa) (Zinc finger transcription factor TReP-132) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000124496 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96PN7 |
| Gene Card | TRERF1 |
| Uniprot ID | Q96PN7 |
| Pfam | PF01448 |
| In ASD | no |
| Allosteric Prediction | no (-0.028793864) |
| Ortholog in Animals | Alpaca_ TRERF1 ( ortholog_one2one ) Dog_ TRERF1 ( ortholog_one2one ) GuineaPig_ TRERF1 ( ortholog_one2one ) Macaque_ TRERF1 ( ortholog_one2one ) Mouse_ Trerf1 ( ortholog_one2one ) Pig_ TRERF1 ( ortholog_one2one ) Rat_ Trerf1 ( ortholog_one2one ) Rabbit_ TRERF1 ( ortholog_one2one ) |
| Ohnologs | ZNF541 |
| Paralogs | MIDEAS, RCOR1, ZNF541, RCOR2, RCOR3 |
| Tissue | NA |
| Tissue Specificity | Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic Hep-G2 and HEK293 cells. {ECO:0000269|PubMed:11349124}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35162277 rs59159203 rs2295275 rs35978318 rs11751765 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624, ECO:0000269|PubMed:11349124, ECO:0000269|PubMed:16371131}. |
| Mouse PG classification | NA |
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