| Gene Information | |
|---|---|
| Gene Name | RAD21L1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 556 |
| Protein Names | Double-strand-break repair protein rad21-like protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000244588 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H4I0 |
| Gene Card | RAD21L1 |
| Uniprot ID | Q9H4I0 |
| Pfam | PF04824; PF04825 |
| In ASD | no |
| Allosteric Prediction | no (-1.501132419) |
| Ortholog in Animals | Alpaca_ SNPH ( ortholog_one2one ) Dog_ RAD21L1 ( ortholog_one2one ) GuineaPig_ RAD21L1 ( ortholog_one2one ) Macaque_ RAD21L1 ( ortholog_one2one ) Mouse_ Rad21l ( ortholog_one2one ) Rat_ Rad21l1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RAD21, REC8 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.038105(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs450739 rs203534 rs17717241 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:A2AU37}. Chromosome {ECO:0000250|UniProtKB:A2AU37}. Note=In meiotic chromosomes, localized along axial elements in early meiosis: detectable on the axial elements in leptotene, and stays on the axial/lateral elements until mid pachytene. It then disappears and is replaced with RAD21. Compared to REC8, has mutually exclusive loading sites on the chromosomes: REC8 and RAD21L form distinct cohesin-enriched domains along the axial elements. {ECO:0000250|UniProtKB:A2AU37}. |
| Mouse PG classification | NA |
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