Gene Information
Gene NameIL17D
OrganismHomo sapiens (Human)
Gene Length202
Protein NamesInterleukin-17D (IL-17D) (Interleukin-27) (IL-27)
Target Nameinterleukin-27
Target TypeClinical trial target
Gene Age454 ( ENSG00000172458 )
Evolutionary StageVertebrata
AlphaFoldDBQ8TAD2
Gene CardIL17D
Uniprot IDQ8TAD2
PfamPF06083
In ASDno
Allosteric Predictionno (-0.823371374)
Ortholog in AnimalsAlpaca_ IL17D ( ortholog_one2one )
Dog_ IL17D ( ortholog_one2one )
GuineaPig_ IL17D ( ortholog_one2one )
Macaque_ IL17D ( ortholog_one2one )
Mouse_ Il17d ( ortholog_one2one )
Pig_ IL17D ( ortholog_one2one )
OhnologsNA
ParalogsIL17F, IL17B, IL17A, IL17C, IL25
Tissuecerebral.cortex, skeletal.muscle
Tissue SpecificityExpressed preferentially in adipose, skeletal muscle and CNS. {ECO:0000269|PubMed:12097364}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Secreted.
Mouse PG classificationNA
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