| Gene Information | |
|---|---|
| Gene Name | IL16 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1332 |
| Protein Names | Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL-16) (Lymphocyte chemoattractant factor) (LCF)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000172349 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q14005 |
| Gene Card | IL16 |
| Uniprot ID | Q14005 |
| Pfam | PF00595 |
| In ASD | no |
| Allosteric Prediction | yes (0.064888789) |
| Ortholog in Animals | Alpaca_ IL16 ( ortholog_one2one ) Dog_ IL16 ( ortholog_one2one ) GuineaPig_ IL16 ( ortholog_one2one ) Macaque_ IL16 ( ortholog_one2one ) Mouse_ Il16 ( ortholog_one2one ) Pig_ IL16 ( ortholog_one2one ) Rat_ Il16 ( ortholog_one2one ) Rabbit_ IL16 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PDZD2 |
| Tissue | NA |
| Tissue Specificity | [Isoform 3]: Expressed in hemopoietic tissues, such as resting T-cells, but undetectable during active T-cell proliferation. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1I16 (NMR - ) 1X6D (NMR - ) 5FB8 (X-ray 2.07A ) |
| DBSNP | rs4072111 rs17875512 rs17875513 rs34101586 rs11556218 rs34159341 |
| Subcellular location [CC] | [Interleukin-16]: Secreted.; [Isoform 1]: Cytoplasm {ECO:0000250}.; [Isoform 3]: Cytoplasm. Nucleus. |
| Mouse PG classification | NA |
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