| Gene Information | |
|---|---|
| Gene Name | IL10R |
| Organism | Homo sapiens (Human) |
| Gene Length | 578 |
| Protein Names | Interleukin-10 receptor subunit alpha (IL-10 receptor subunit alpha) (IL-10R subunit alpha) (IL-10RA) (CDw210a) (Interleukin-10 receptor subunit 1) (IL-10R subunit 1) (IL-10R1) (CD antigen CD210) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q13651 |
| Gene Card | IL10RA |
| Uniprot ID | Q13651 |
| Pfam | PF01108 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Primarily expressed in hematopoetic cells including B-cells, T-cells, NK cells, monocytes and macrophages. Not expressed in non-hematopoetic cells such as fibroblasts or endothelial cells. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.010990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1J7V (X-ray 2.90A ) 1LQS (X-ray 2.70A ) 1Y6K (X-ray 2.52A ) 1Y6M (X-ray 2.80A ) 1Y6N (X-ray 2.70A ) 5IXI (X-ray 2.57A ) 6X93 (EM 3.50A ) |
| DBSNP | rs4252250 rs1343534194 rs137853580 rs1591261607 rs368287711 rs4252303 rs199989396 rs137853579 rs3135932 rs4252273 rs2228055 rs149491038 rs2229113 rs35235073 rs2229114 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:22087322, ECO:0000269|PubMed:26962683}; Single-pass type I membrane protein. Cytoplasm {ECO:0000269|PubMed:26962683}. |
| Mouse PG classification | NA |
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