| Gene Information | |
|---|---|
| Gene Name | IFT20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 132 |
| Protein Names | Intraflagellar transport protein 20 homolog (hIFT20) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000109083 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8IY31 |
| Gene Card | IFT20 |
| Uniprot ID | Q8IY31 |
| Pfam | PF14931 |
| In ASD | no |
| Allosteric Prediction | no (-1.484359049) |
| Ortholog in Animals | Alpaca_ IFT20 ( ortholog_one2one ) Dog_ IFT20 ( ortholog_one2one ) GuineaPig_ IFT20 ( ortholog_one2one ) Macaque_ IFT20 ( ortholog_one2one ) Mouse_ Ift20 ( ortholog_one2one ) Pig_ IFT20 ( ortholog_one2one ) Rat_ Ift20 ( ortholog_one2one ) Rabbit_ IFT20 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in almost all tissues. {ECO:0000269|PubMed:14672413}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001759(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus, cis-Golgi network {ECO:0000250|UniProtKB:Q61025}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q61025}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q61025}. Cell projection, cilium {ECO:0000250|UniProtKB:Q61025}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q61025}. Golgi apparatus {ECO:0000250|UniProtKB:Q61025}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q61025}. Cytoplasm {ECO:0000250|UniProtKB:Q61025}. Note=Present at the centrosomes during the cell cycle and associated with the proximal portion of the mother centriole and the lateral aspect of the daughter centriole. Associated with basal body at the base of primary cilia. Detected in the Golgi apparatus of round spermatids and late spermatocytes. Also detected in the manchette of step 10-12 spermatids. In step 14 spermatids, found in the basal body of the sperm tail. Localization in the manchette of elongating spermatids is dependent on SPAG17. {ECO:0000250|UniProtKB:Q61025}. |
| Mouse PG classification | NA |
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