| Gene Information | |
|---|---|
| Gene Name | IGSF6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 241 |
| Protein Names | Immunoglobulin superfamily member 6 (IgSF6) (Protein DORA) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000140749 ) 3 ( ENSG00000283934 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O95976 |
| Gene Card | IGSF6 |
| Uniprot ID | O95976 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-0.484741075) |
| Ortholog in Animals | Alpaca_ IGSF6 ( ortholog_one2one ) GuineaPig_ IGSF6 ( ortholog_one2one ) Macaque_ IGSF6 ( ortholog_one2one ) Mouse_ Igsf6 ( ortholog_one2one ) Pig_ IGSF6 ( ortholog_one2one ) Rat_ Igsf6 ( ortholog_one2one ) Rabbit_ IGSF6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | lung, spleen, whole.blood |
| Tissue Specificity | Expressed in peripheral blood lymphocytes, spleen and lymph node, with low levels in thymus, bone marrow and fetal liver. No expression in non-immune tissues. {ECO:0000269|PubMed:9809579}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17851574 rs2290612 rs751849987 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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