| Gene Information | |
|---|---|
| Gene Name | LHPP |
| Organism | Homo sapiens (Human) |
| Gene Length | 270 |
| Protein Names | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (hLHPP) (EC 3.1.3.-) (EC 3.6.1.1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000107902 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9H008 |
| Gene Card | LHPP |
| Uniprot ID | Q9H008 |
| Pfam | PF13344 |
| In ASD | no |
| Allosteric Prediction | no (-0.313030605) |
| Ortholog in Animals | Alpaca_ LHPP ( ortholog_one2one ) Dog_ LHPP ( ortholog_one2one ) GuineaPig_ LHPP ( ortholog_one2one ) Macaque_ LHPP ( ortholog_one2one ) Mouse_ Lhpp ( ortholog_one2one ) Pig_ LHPP ( ortholog_one2one ) Rat_ Lhpp ( ortholog_one2one ) Rabbit_ LHPP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PDXP, PGP, HDHD2 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, and at lower levels in liver and kidney. Detected in thyroid (at protein level). Expressed in liver, kidney and moderately in brain. {ECO:0000269|PubMed:12801912, ECO:0000269|PubMed:16430861}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2X4D (X-ray 1.92A ) |
| DBSNP | rs6597801 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16430861}. Nucleus {ECO:0000269|PubMed:16430861}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |