| Gene Information | |
|---|---|
| Gene Name | GIMAP6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 292 |
| Protein Names | GTPase IMAP family member 6 (Immunity-associated nucleotide 2 protein) (IAN-2) (hIAN2) (Immunity-associated nucleotide 6 protein) (IAN-6) (hIAN6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000133561 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6P9H5 |
| Gene Card | GIMAP6 |
| Uniprot ID | Q6P9H5 |
| Pfam | PF04548 |
| In ASD | no |
| Allosteric Prediction | no (-1.566292432) |
| Ortholog in Animals | Alpaca_ GIMAP6 ( ortholog_one2many ) Dog_ GIMAP6 ( ortholog_one2one ) GuineaPig_ GIMAP6 ( ortholog_one2one ) Macaque_ GIMAP6 ( ortholog_one2one ) Mouse_ Gimap6 ( ortholog_one2one ) Rat_ Gimap6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GIMAP5, GIMAP4, GIMD1, GIMAP1, GIMAP2, GIMAP7, GIMAP8 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in spleen, lymph nodes, lung and placenta. Expressed at moderate level in thymus, kidney, heart and digestive tract. Weakly expressed in other lymphoid tissues. Detected in T-cells. {ECO:0000269|PubMed:15474311, ECO:0000269|PubMed:23454188}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs17173519 rs11974345 rs13234724 rs11977216 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:23454188}. |
| Mouse PG classification | NA |
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