| Gene Information | |
|---|---|
| Gene Name | IGSF3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1194 |
| Protein Names | Immunoglobulin superfamily member 3 (IgSF3) (Glu-Trp-Ile EWI motif-containing protein 3) (EWI-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000143061 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O75054 |
| Gene Card | IGSF3 |
| Uniprot ID | O75054 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-1.017744273) |
| Ortholog in Animals | Alpaca_ IGSF3 ( ortholog_one2one ) Dog_ IGSF3 ( ortholog_one2one ) GuineaPig_ IGSF3 ( ortholog_one2one ) Macaque_ IGSF3 ( ortholog_one2one ) Mouse_ Igsf3 ( ortholog_one2one ) Pig_ IGSF3 ( ortholog_one2one ) Rat_ Igsf3 ( ortholog_one2one ) Rabbit_ IGSF3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | VSTM4, IGSF8, PTGFRN, VSTM2A, CD101 |
| Tissue | NA |
| Tissue Specificity | Expressed in a wide range of tissues with High expression in Placenta, kidney and lung. {ECO:0000269|PubMed:9790749}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3965246 rs647711 rs6703791 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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