| Gene Information | |
|---|---|
| Gene Name | FBLN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 703 |
| Protein Names | Fibulin-1 (FIBL-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000077942 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P23142 |
| Gene Card | FBLN1 |
| Uniprot ID | P23142 |
| Pfam | PF12662; PF07645 |
| In ASD | no |
| Allosteric Prediction | no (-0.172215569) |
| Ortholog in Animals | Alpaca_ FBLN1 ( ortholog_one2one ) Dog_ FBLN1 ( ortholog_one2one ) GuineaPig_ FBLN1 ( ortholog_one2one ) Macaque_ FBLN1 ( ortholog_one2one ) Mouse_ Fbln1 ( ortholog_one2one ) Pig_ FBLN1 ( ortholog_one2one ) Rat_ Fbln1 ( ortholog_one2one ) Rabbit_ FBLN1 ( ortholog_one2one ) |
| Ohnologs | FBLN2, EFEMP2 |
| Paralogs | VWDE, EFEMP1, FBLN5, FBLN2, EFEMP2, EYS |
| Tissue | NA |
| Tissue Specificity | Isoform A and isoform B are only expressed in placenta. Isoform C and isoform D are expressed in a variety of tissues and cultured cells. {ECO:0000269|PubMed:9106159}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs136730 rs397509432 rs1802787 rs13268 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix. |
| Mouse PG classification | LPG |
| click here to return to the previous page | |