| Gene Information | |
|---|---|
| Gene Name | IGLL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 213 |
| Protein Names | Immunoglobulin lambda-like polypeptide 1 (CD179 antigen-like family member B) (Ig lambda-5) (Immunoglobulin omega polypeptide) (Immunoglobulin-related protein 14.1) (CD antigen CD179b) |
| Target Name | immunoglobulin lambda-like polypeptide 1 |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000128322 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P15814 |
| Gene Card | IGLL1 |
| Uniprot ID | P15814 |
| Pfam | PF07654 |
| In ASD | no |
| Allosteric Prediction | no (-1.037134007) |
| Ortholog in Animals | Mouse_ Iglc4 ( ortholog_many2many ) Mouse_ Iglc3 ( ortholog_many2many ) Mouse_ Iglc2 ( ortholog_many2many ) Mouse_ Iglc1 ( ortholog_many2many ) Rat_ AABR07034739.1 ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | TRDC, IGHV4OR15-8, IGHV4-4, IGHV4-61, IGHV4-59, IGHV4-39, IGHV4-31, IGHV4-28, IGHV4-34, IGHV6-1, IGHV2-5, IGHV2OR16-5, IGHV2-26, IGHV2-70D, IGHV2-70, IGKC, IGHV5-51, IGHV5-10-1, IGHV1-69-2, IGHV1-24, IGHV1-3, IGHV1-58, IGHV1-45, IGHV1-18, IGHV1-69, IGHV1-69D, IGHV1-2, IGHV1OR15-1, IGHV1-46, IGHV1OR15-9, IGHV1OR21-1, IGHV3OR16-9, IGHV3OR16-8, IGHV3OR16-17, IGHV3-35, IGHV3-16, IGHV7-81, IGHV7-4-1, IGHG3, IGHG1, IGHG2, IGHG4, IGHE, IGHM, IGHV3-13, IGHV3OR16-10, IGHV3-48, IGHV3-21, IGHV3-11, IGHV3-43, IGHV3-20, IGHV3-74, IGHV3OR16-13, IGHV3-73, IGHV3-72, IGHV3OR15-7, IGHV3-15, IGHV3-49, IGHV3-30, IGHV3-33, IGHV3-7, IGHV8-51-1, IGHV3-64D, IGHV3-64, IGHV3-23, IGHV3-66, IGHV3-53, IGHV3-38, IGHV3OR16-12, IGHA1, IGHA2, IGHD, IGLL5, IGLC3, IGLC7, IGLC2, IGLC1 |
| Tissue | bone.marrow, testis |
| Tissue Specificity | Expressed only in pre-B-cells and a special B-cell line (which is surface Ig negative). {ECO:0000269|PubMed:2128466}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2H32 (X-ray 2.70A ) 2H3N (X-ray 2.30A ) 2LKQ (NMR - ) |
| DBSNP | rs1064422 rs8138122 |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000250|UniProtKB:P20764}. Secreted {ECO:0000269|PubMed:9419212}. Note=In pre-B cells, localizes predominantly to the endoplasmic reticulum. {ECO:0000250|UniProtKB:P20764}. |
| Mouse PG classification | NA |
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