| Gene Information | |
|---|---|
| Gene Name | UNQ323/PRO382 |
| Organism | Homo sapiens (Human) |
| Gene Length | 454 |
| Protein Names | Transmembrane protease serine 3 (EC 3.4.21.-) (Serine protease TADG-12) (Tumor-associated differentially-expressed gene 12 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P57727 |
| Gene Card | TMPRSS3 |
| Uniprot ID | P57727 |
| Pfam | PF00057; PF15494; PF00089 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs928302 rs387906915 rs201632198 rs35227181 rs766000719 rs1333651774 rs137853000 rs137852999 rs2839500 rs28939084 rs773780151 rs56264519 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12393794}; Single-pass type II membrane protein {ECO:0000269|PubMed:12393794}. |
| Mouse PG classification | NA |
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