| Gene Information | |
|---|---|
| Gene Name | IGKC |
| Organism | Homo sapiens (Human) |
| Gene Length | 107 |
| Protein Names | Immunoglobulin kappa constant (Ig kappa chain C region) (Ig kappa chain C region AG) (Ig kappa chain C region CUM) (Ig kappa chain C region EU) (Ig kappa chain C region OU) (Ig kappa chain C region ROY) (Ig kappa chain C region TI) |
| Target Name | ig kappa chain c region |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000211592 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | P01834 |
| Gene Card | IGKC |
| Uniprot ID | P01834 |
| Pfam | PF07654 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | Alpaca_ IGKC ( ortholog_one2one ) Macaque_ IGKC ( ortholog_one2one ) Mouse_ Igkc ( ortholog_one2one ) Rat_ AABR07060872.1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TRDC, IGHV4OR15-8, IGHV4-4, IGHV4-61, IGHV4-59, IGHV4-39, IGHV4-31, IGHV4-28, IGHV4-34, IGHV6-1, IGHV2-5, IGHV2OR16-5, IGHV2-26, IGHV2-70D, IGHV2-70, IGHV5-51, IGHV5-10-1, IGHV1-69-2, IGHV1-24, IGHV1-3, IGHV1-58, IGHV1-45, IGHV1-18, IGHV1-69, IGHV1-69D, IGHV1-2, IGHV1OR15-1, IGHV1-46, IGHV1OR15-9, IGHV1OR21-1, IGHV3OR16-9, IGHV3OR16-8, IGHV3OR16-17, IGHV3-35, IGHV3-16, IGLL1, IGLC7, IGLC3, IGLC2, IGLC1, IGLL5, IGHV7-81, IGHV7-4-1, IGHG3, IGHG1, IGHG2, IGHG4, IGHE, IGHM, IGHV3-13, IGHV3OR16-10, IGHV3-48, IGHV3-21, IGHV3-11, IGHV3-43, IGHV3-20, IGHV3-74, IGHV3OR16-13, IGHV3-73, IGHV3-72, IGHV3OR15-7, IGHV3-15, IGHV3-49, IGHV3-30, IGHV3-33, IGHV3-7, IGHV8-51-1, IGHV3-64D, IGHV3-64, IGHV3-23, IGHV3-66, IGHV3-53, IGHV3-38, IGHV3OR16-12, IGHA1, IGHA2, IGHD |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1A4J (X-ray 2.10A ) 1A4K (X-ray 2.40A ) 1CLY (X-ray 2.50A ) 1D5B (X-ray 2.80A ) 1D5I (X-ray 2.00A ) 1D6V (X-ray 2.00A ) 1DFB (X-ray 2.70A ) 1GAF (X-ray 1.95A ) 1HEZ (X-ray 2.70A ) 1HKL (X-ray 2.68A ) 1HZH (X-ray 2.70A ) 1I7Z (X-ray 2.30A ) 1MIM (X-ray 2.60A ) 1N0X (X-ray 1.80A ) 1UCB (X-ray 2.50A ) 2NY7 (X-ray 2.30A ) 2O5X (X-ray 2.05A ) 2O5Y (X-ray 2.85A ) 2O5Z (X-ray 2.40A ) 2QQK (X-ray 2.75A ) 2QQL (X-ray 3.10A ) 2QQN (X-ray 2.20A ) 2QSC (X-ray 2.80A ) 2R56 (X-ray 2.80A ) 2RFX (X-ray 2.50A ) 2VXQ (X-ray 1.90A ) 3B2U (X-ray 2.58A ) 3B2V (X-ray 3.30A ) 3BDY (X-ray 2.60A ) 3BE1 (X-ray 2.90A ) 3BKY (X-ray 2.61A ) 3BN9 (X-ray 2.17A ) 3BQU (X-ray 3.00A ) 3C08 (X-ray 2.15A ) 3C09 (X-ray 3.20A ) 3CFJ (X-ray 2.60A ) 3CFK (X-ray 2.60A ) 3CSY (X-ray 3.40A ) 3D0L (X-ray 2.35A ) 3D85 (X-ray 1.90A ) 3DVG (X-ray 2.60A ) 3DVN (X-ray 2.70A ) 3EYF (X-ray 2.30A ) 3EYO (X-ray 2.50A ) 3EYQ (X-ray 2.40A ) 3IU3 (X-ray 2.90A ) 3O11 (X-ray 2.80A ) 3QCT (X-ray 2.15A ) 3QCU (X-ray 1.98A ) 3QCV (X-ray 2.51A ) 3RU8 (X-ray 2.07A ) 3U0W (X-ray 2.00A ) 3U7W (X-ray 2.60A ) 3U7Y (X-ray 2.45A ) 3VH8 (X-ray 1.80A ) 3WUW (X-ray 2.00A ) 3X11 (X-ray 2.15A ) 3X12 (X-ray 1.80A ) 4D3C (X-ray 2.62A ) 4D9R (X-ray 2.42A ) 4HIX (X-ray 2.20A ) 4NM4 (X-ray 2.65A ) 4NM8 (X-ray 4.00A ) 4XMP (X-ray 1.78A ) 4XNY (X-ray 2.30A ) 4XNZ (X-ray 3.39A ) 4XXD (X-ray 2.41A ) 4YDV (X-ray 2.70A ) 5B38 (X-ray 2.30A ) 5B39 (X-ray 2.50A ) 5C7K (X-ray 4.60A ) 5ESV (X-ray 3.10A ) 5ESZ (X-ray 4.19A ) 5EWI (X-ray 1.60A ) 5VEB (X-ray 2.34A ) 5VIY (EM 6.20A ) 6AU5 (X-ray 2.48A ) 6AXP (X-ray 2.48A ) 6AYN (X-ray 2.48A ) 6AZK (X-ray 2.48A ) 6AZL (X-ray 2.48A ) 6B9Y (X-ray 2.14A ) 6B9Z (X-ray 1.82A ) 6BAE (X-ray 2.14A ) 6BAH (X-ray 1.90A ) 6DCV (X-ray 1.90A ) 6DCW (X-ray 2.00A ) 6N2X (X-ray 3.00A ) 6N32 (X-ray 2.20A ) 6N35 (X-ray 1.75A ) 6OGE (EM 4.36A ) 6OKP (EM 3.28A ) 7CZY (EM 3.30A ) 7CZZ (EM 3.20A ) 7XQ8 (EM 3.30A ) 8DAO (X-ray 2.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}. Cell membrane {ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}. |
| Mouse PG classification | NA |
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