| Gene Information | |
|---|---|
| Gene Name | PIK3AP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 805 |
| Protein Names | Phosphoinositide 3-kinase adapter protein 1 (B-cell adapter for phosphoinositide 3-kinase) (B-cell phosphoinositide 3-kinase adapter protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000155629 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6ZUJ8 |
| Gene Card | PIK3AP1 |
| Uniprot ID | Q6ZUJ8 |
| Pfam | PF14545; PF18567 |
| In ASD | no |
| Allosteric Prediction | no (-0.280419606) |
| Ortholog in Animals | Alpaca_ PIK3AP1 ( ortholog_one2one ) Dog_ PIK3AP1 ( ortholog_one2one ) GuineaPig_ PIK3AP1 ( ortholog_one2one ) Macaque_ PIK3AP1 ( ortholog_one2one ) Mouse_ Pik3ap1 ( ortholog_one2one ) Pig_ PIK3AP1 ( ortholog_one2one ) Rat_ Pik3ap1 ( ortholog_one2one ) Rabbit_ PIK3AP1 ( ortholog_one2one ) |
| Ohnologs | BANK1 |
| Paralogs | BANK1 |
| Tissue | liver, spleen, whole.blood |
| Tissue Specificity | Expressed in natural killer (NK) cells. {ECO:0000269|PubMed:18337558}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5FOR (X-ray 2.50A ) 6SWS (X-ray 3.00A ) |
| DBSNP | rs17112076 rs3748229 rs3748233 rs12784975 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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