| Gene Information | |
|---|---|
| Gene Name | IGFR3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 233 |
| Protein Names | Low affinity immunoglobulin gamma Fc region receptor III-B (Fc-gamma RIII-beta) (CD16-I) (Fc-gamma RIII) (Fc-gamma RIIIb) (FcRIII) (FcRIIIb) (FcR-10) (IgG Fc receptor III-1) (CD antigen CD16b) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O75015 |
| Gene Card | FCGR3B |
| Uniprot ID | O75015 |
| Pfam | PF13895 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed specifically by polymorphonuclear leukocytes (neutrophils). Also expressed by stimulated eosinophils. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1E4J (X-ray 2.50A ) 1E4K (X-ray 3.20A ) 1FNL (X-ray 1.80A ) 1T83 (X-ray 3.00A ) 1T89 (X-ray 3.50A ) 6EAQ (X-ray 2.22A ) |
| DBSNP | rs200688856 rs448740 rs5030738 rs147574249 rs2290834 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:1825220}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:1825220}. Secreted. Note=Secreted after cleavage. |
| Mouse PG classification | NA |
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