| Gene Information | |
|---|---|
| Gene Name | IGFBPL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 278 |
| Protein Names | Insulin-like growth factor-binding protein-like 1 (IGFBP-related protein 10) (Insulin-like growth factor-binding-related protein 4) (IGFBP-rP4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000137142 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8WX77 |
| Gene Card | IGFBPL1 |
| Uniprot ID | Q8WX77 |
| Pfam | PF07679; PF00219; PF07648 |
| In ASD | no |
| Allosteric Prediction | no (-1.808957866) |
| Ortholog in Animals | Alpaca_ IGFBPL1 ( ortholog_one2one ) GuineaPig_ IGFBPL1 ( ortholog_one2one ) Macaque_ IGFBPL1 ( ortholog_one2one ) Mouse_ Igfbpl1 ( ortholog_one2one ) Pig_ IGFBPL1 ( ortholog_one2one ) Rat_ Igfbpl1 ( ortholog_one2one ) Rabbit_ IGFBPL1 ( ortholog_one2one ) |
| Ohnologs | KAZALD1 |
| Paralogs | IGFBP7, KAZALD1 |
| Tissue | thyroid, brain |
| Tissue Specificity | Expressed at the highest level in both brain and testis, with lower levels in the prostate, bladder and lung. {ECO:0000269|PubMed:15845387}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7MJ6 (X-ray 1.95A ) 7MJ7 (X-ray 1.60A ) 7MJ8 (X-ray 1.79A ) 7MJ9 (X-ray 1.75A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:15845387}. |
| Mouse PG classification | NA |
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