| Gene Information | |
|---|---|
| Gene Name | IGFBP5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 272 |
| Protein Names | Insulin-like growth factor-binding protein 5 (IBP-5) (IGF-binding protein 5) (IGFBP-5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000115461 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P24593 |
| Gene Card | IGFBP5 |
| Uniprot ID | P24593 |
| Pfam | PF00219; PF00086 |
| In ASD | no |
| Allosteric Prediction | no (-0.18727417) |
| Ortholog in Animals | Alpaca_ IGFBP5 ( ortholog_one2one ) Dog_ IGFBP5 ( ortholog_one2one ) GuineaPig_ IGFBP5 ( ortholog_one2one ) Macaque_ IGFBP5 ( ortholog_one2one ) Mouse_ Igfbp5 ( ortholog_one2one ) Pig_ IGFBP5 ( ortholog_one2one ) Rat_ Igfbp5 ( ortholog_one2one ) Rabbit_ IGFBP5 ( ortholog_one2one ) |
| Ohnologs | IGFBP4, IGFBP3, IGFBP1, IGFBP6 |
| Paralogs | IGFBP6, IGFBP3, IGFBP2, IGFBP1, IGFBP4 |
| Tissue | NA |
| Tissue Specificity | Osteosarcoma, and at lower levels in liver, kidney and brain. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005990(Rat);0.100000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1BOE (NMR - ) 1H59 (X-ray 2.10A ) |
| DBSNP | rs11575194 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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