| Gene Information | |
|---|---|
| Gene Name | IGFALS |
| Organism | Homo sapiens (Human) |
| Gene Length | 605 |
| Protein Names | Insulin-like growth factor-binding protein complex acid labile subunit (ALS) |
| Target Name | insulin-like growth factor-binding protein complex acid labile subunit |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000099769 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P35858 |
| Gene Card | IGFALS |
| Uniprot ID | P35858 |
| Pfam | PF13855; PF01462 |
| In ASD | no |
| Allosteric Prediction | yes (0.019750841) |
| Ortholog in Animals | Alpaca_ IGFALS ( ortholog_one2one ) Dog_ IGFALS ( ortholog_one2one ) GuineaPig_ IGFALS ( ortholog_one2one ) Macaque_ IGFALS ( ortholog_one2one ) Mouse_ Igfals ( ortholog_one2one ) Pig_ IGFALS ( ortholog_one2one ) Rat_ Igfals ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CD180, RXFP1, TLR8, NRROS, TLR5, TSKU, TLR7, TLR10, RXFP2, TLR6, LRRC3B, TLR3, TLR2, TLR4, LRRC17, LRRC32, LRRC53, VASN, TLR1, LRRC3C, LRRC3, LRIT2 |
| Tissue | liver |
| Tissue Specificity | Plasma. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7WRQ (EM 3.60A ) |
| DBSNP | rs766004600 rs35947557 rs774634302 rs551618643 rs34297640 rs776840046 rs9282730 rs121909247 rs9282731 |
| Subcellular location [CC] | Secreted, extracellular space. |
| Mouse PG classification | LPG |
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