| Gene Information | |
|---|---|
| Gene Name | HS3ST3A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 406 |
| Protein Names | Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (3-OST-3A) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A) |
| Target Name | heparan sulfate glucosamine 3-o-sulfotransferase 3a1 |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000153976 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9Y663 |
| Gene Card | HS3ST3A1 |
| Uniprot ID | Q9Y663 |
| Pfam | PF00685 |
| In ASD | no |
| Allosteric Prediction | no (-0.721232487) |
| Ortholog in Animals | Alpaca_ HS3ST3A1 ( ortholog_one2one ) Dog_ HS3ST3A1 ( ortholog_one2one ) GuineaPig_ HS3ST3A1 ( ortholog_one2one ) Macaque_ HS3ST3A1 ( ortholog_one2one ) Mouse_ Hs3st3a1 ( ortholog_one2one ) Pig_ HS3ST3A1 ( ortholog_one2one ) Rat_ Hs3st3a1 ( ortholog_one2one ) Rabbit_ HS3ST3A1 ( ortholog_one2one ) |
| Ohnologs | HS3ST2, HS3ST6, HS3ST4 |
| Paralogs | NDST1, HS3ST1, HS3ST4, HS3ST2, NDST3, HS3ST6, NDST4, NDST2, HS3ST3B1, HS3ST5 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Most abundant in heart and placenta, followed by liver and kidney. {ECO:0000269|PubMed:9988767}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1T8T (X-ray 1.85A ) 1T8U (X-ray 1.95A ) 6XKG (X-ray 1.55A ) 6XL8 (X-ray 2.34A ) |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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