| Gene Information | |
|---|---|
| Gene Name | IFT81 |
| Organism | Homo sapiens (Human) |
| Gene Length | 676 |
| Protein Names | Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000122970 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q8WYA0 |
| Gene Card | IFT81 |
| Uniprot ID | Q8WYA0 |
| Pfam | PF18383 |
| In ASD | no |
| Allosteric Prediction | no (-1.456948498) |
| Ortholog in Animals | Alpaca_ IFT81 ( ortholog_one2one ) Dog_ IFT81 ( ortholog_one2one ) GuineaPig_ IFT81 ( ortholog_one2one ) Macaque_ IFT81 ( ortholog_one2one ) Mouse_ Ift81 ( ortholog_one2one ) Pig_ IFT81 ( ortholog_one2one ) Rat_ Ift81 ( ortholog_one2one ) Rabbit_ IFT81 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in testis, moderately in ovary, heart, liver, skeletal muscle, kidney and pancreas, low in prostate, brain, placenta and lung and not detected in spleen, thymus, small intestine and colon. Isoform CDV-1R is abundantly expressed in testis. {ECO:0000269|PubMed:12549821}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.138462(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs751222088 |
| Subcellular location [CC] | Cell projection, cilium {ECO:0000305|PubMed:23990561}. Cytoplasm {ECO:0000250|UniProtKB:O35594}. |
| Mouse PG classification | NA |
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