Gene Information
Gene NameP2RY6
OrganismHomo sapiens (Human)
Gene Length328
Protein NamesP2Y purinoceptor 6 (P2Y6)
Target Namep2y purinoceptor 6
Target TypeClinical trial target
Gene Age454 ( ENSG00000171631 )
Evolutionary StageVertebrata
AlphaFoldDBQ15077
Gene CardP2RY6
Uniprot IDQ15077
PfamPF00001
In ASDyes
Allosteric Predictionyes (0.721594302)
Ortholog in AnimalsAlpaca_ P2RY6 ( ortholog_one2one )
Dog_ P2RY6 ( ortholog_one2one )
GuineaPig_ P2RY6 ( ortholog_one2one )
Macaque_ P2RY6 ( ortholog_one2one )
Mouse_ P2ry6 ( ortholog_one2one )
Pig_ P2RY6 ( ortholog_one2one )
Rat_ P2ry6 ( ortholog_one2one )
Rabbit_ P2RY6 ( ortholog_one2one )
OhnologsNA
ParalogsFFAR3, GPR42, FFAR2, GPR82, GPR31, FFAR1, HCAR3, HCAR1, HCAR2, OXER1, P2RY2, P2RY4, P2RY1, OXGR1, SUCNR1
Tissueplacenta, spleen
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cell membrane;
Multi-pass membrane protein.
Mouse PG classificationNA
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