| Gene Information | |
|---|---|
| Gene Name | IFP35 |
| Organism | Homo sapiens (Human) |
| Gene Length | 286 |
| Protein Names | Interferon-induced 35 kDa protein (IFP 35) (Ifi-35) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P80217 |
| Gene Card | IFI35 |
| Uniprot ID | P80217 |
| Pfam | PF07334; PF07292 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in a wide range of cell types, including fibroblasts, macrophages, and epithelial cells. {ECO:0000269|PubMed:29038465, ECO:0000269|PubMed:8288566}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs588703 rs588703 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10779520, ECO:0000269|PubMed:10950963, ECO:0000269|PubMed:8288566}. Nucleus {ECO:0000269|PubMed:10950963, ECO:0000269|PubMed:26342464, ECO:0000269|PubMed:8288566}. Secreted {ECO:0000269|PubMed:29038465}. Note=Cytoplasmic IFI35 localizes in punctate granular structures (PubMed:10950963). Nuclear localization increased is stimulated by IFN-alpha (PubMed:8288566, PubMed:10950963). Extracelullar following secretion by macrophage (PubMed:29038465). {ECO:0000269|PubMed:10950963, ECO:0000269|PubMed:29038465, ECO:0000269|PubMed:8288566}. |
| Mouse PG classification | NA |
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