| Gene Information | |
|---|---|
| Gene Name | IFNLR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 520 |
| Protein Names | Interferon lambda receptor 1 (IFN-lambda receptor 1) (IFN-lambda-R1) (Cytokine receptor class-II member 12) (Cytokine receptor family 2 member 12) (CRF2-12) (Interleukin-28 receptor subunit alpha) (IL-28 receptor subunit alpha) (IL-28R-alpha) (IL-28RA) (Likely interleukin or cytokine receptor 2) (LICR2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000185436 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8IU57 |
| Gene Card | IFNLR1 |
| Uniprot ID | Q8IU57 |
| Pfam | PF01108 |
| In ASD | no |
| Allosteric Prediction | no (-0.246405358) |
| Ortholog in Animals | Alpaca_ IFNLR1 ( ortholog_one2one ) Dog_ IFNLR1 ( ortholog_one2one ) GuineaPig_ IFNLR1 ( ortholog_one2one ) Macaque_ IFNLR1 ( ortholog_one2one ) Mouse_ Ifnlr1 ( ortholog_one2one ) Pig_ IFNLR1 ( ortholog_one2one ) Rat_ Ifnlr1 ( ortholog_one2one ) Rabbit_ IFNLR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IFNAR1, IL22RA2, IFNGR2, IL22RA1, F3, IL10RA, IL20RB, IL20RA, IFNAR2, IFNGR1, IL10RB |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:12469119, ECO:0000269|PubMed:12483210}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3OG4 (X-ray 2.16A ) 3OG6 (X-ray 2.10A ) 5IXD (X-ray 2.85A ) 5IXI (X-ray 2.57A ) 5L04 (X-ray 2.10A ) 5T5W (X-ray 2.85A ) |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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