| Gene Information | |
|---|---|
| Gene Name | SYT5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 386 |
| Protein Names | Synaptotagmin-5 (Synaptotagmin V) (SytV) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000129990 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O00445 |
| Gene Card | SYT5 |
| Uniprot ID | O00445 |
| Pfam | PF00168 |
| In ASD | no |
| Allosteric Prediction | no (-0.165261943) |
| Ortholog in Animals | Alpaca_ SYT5 ( ortholog_one2one ) Dog_ SYT5 ( ortholog_one2one ) GuineaPig_ SYT5 ( ortholog_one2one ) Macaque_ SYT5 ( ortholog_one2one ) Mouse_ Syt5 ( ortholog_one2one ) Pig_ SYT5 ( ortholog_one2one ) Rat_ Syt5 ( ortholog_one2one ) |
| Ohnologs | SYT1, SYT2 |
| Paralogs | SYT2, SYTL3, SYT13, TC2N, SYT1, SYT7, SYTL4, SYTL5, DOC2B, DOC2A, SYT14, C2CD4C, SYTL1, RPH3A, SYT8, SYT4, SYT11, SYT12, C2CD4A, C2CD4B, RPH3AL, SYT15, SYT15B, SYT9, SYT16, SYT6, C2CD4D, SYT3, SYTL2, SYT10, SYT17 |
| Tissue | brain, cerebral.cortex, amygdala, caudate.nucleus, hippocampus, hypothalamus, nucleus.accumbens, pituitary.gland, putamen |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5H4Y (X-ray 1.90A ) 5H4Z (X-ray 3.01A ) |
| DBSNP | rs2301279 rs11542503 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Recycling endosome membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=In mast cells, localizes to the endocytic recycling compartment. {ECO:0000250}. |
| Mouse PG classification | NA |
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