| Gene Information | |
|---|---|
| Gene Name | IFNA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 188 |
| Protein Names | Interferon alpha-2 (IFN-alpha-2) (Interferon alpha-A) (LeIF A) |
| Target Name | interferon-alpha 2 |
| Target Type | Successful target |
| Gene Age | 382 ( ENSG00000188379 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P01563 |
| Gene Card | IFNA2 |
| Uniprot ID | P01563 |
| Pfam | PF00143 |
| In ASD | yes |
| Allosteric Prediction | yes (0.805017041) |
| Ortholog in Animals | Alpaca_ IFNA2 ( ortholog_one2one ) Dog_ IFNA7 ( ortholog_many2many ) Dog_ IFNA5 ( ortholog_many2many ) Mouse_ Ifna2 ( ortholog_many2many ) Mouse_ Ifnab ( ortholog_many2many ) Mouse_ Ifna4 ( ortholog_many2many ) Mouse_ Ifna13 ( ortholog_many2many ) Mouse_ Ifna7 ( ortholog_many2many ) Mouse_ Ifna12 ( ortholog_many2many ) Mouse_ Ifna6 ( ortholog_many2many ) Mouse_ Ifna5 ( ortholog_many2many ) Mouse_ Ifna14 ( ortholog_many2many ) Mouse_ Ifna11 ( ortholog_many2many ) Mouse_ Ifna9 ( ortholog_many2many ) Mouse_ Ifna1 ( ortholog_many2many ) Mouse_ Ifna15 ( ortholog_many2many ) Mouse_ Ifna16 ( ortholog_many2many ) Pig_ IFN-ALPHA-10 ( ortholog_many2many ) Pig_ IFNA1 ( ortholog_many2many ) Pig_ IFN-ALPHA-1 ( ortholog_many2many ) Pig_ IFN-ALPHA-17 ( ortholog_many2many ) Pig_ IFN-ALPHA-4 ( ortholog_many2many ) Pig_ IFN-ALPHA-13 ( ortholog_many2many ) Pig_ IFN-ALPHA-9 ( ortholog_many2many ) Rat_ Ifna4 ( ortholog_many2many ) Rat_ RGD1560539 ( ortholog_many2many ) Rat_ Ifna1 ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | IFNA14, IFNA1, IFNA13, IFNA6, IFNA5, IFNA8, IFNA21, IFNA17, IFNA4, IFNA7, IFNA16, IFNA10, IFNW1, IFNE, IFNB1, IFNK |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1ITF (NMR - ) 1RH2 (X-ray 2.90A ) 2HYM (NMR - ) 2KZ1 (NMR - ) 2LAG (NMR - ) 2LMS (NMR - ) 3S9D (X-ray 2.00A ) 3SE3 (X-ray 4.00A ) 4YPG (X-ray 3.00A ) 4Z5R (X-ray 3.00A ) |
| DBSNP | rs35971916 rs1061959 rs73420190 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:6159538}. |
| Mouse PG classification | NA |
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