| Gene Information | |
|---|---|
| Gene Name | OR51E2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 320 |
| Protein Names | Olfactory receptor 51E2 (HPRAJ) (Olfactory receptor OR11-16) (Prostate-specific G-protein coupled receptor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000167332 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9H255 |
| Gene Card | OR51E2 |
| Uniprot ID | Q9H255 |
| Pfam | PF13853 |
| In ASD | no |
| Allosteric Prediction | yes (0.300030618) |
| Ortholog in Animals | Alpaca_ OR51E2 ( ortholog_one2one ) Dog_ OR51E2 ( ortholog_one2one ) GuineaPig_ OR51E2 ( ortholog_one2one ) Macaque_ OR51E2 ( ortholog_one2one ) Mouse_ Olfr78 ( ortholog_one2one ) Pig_ OR51E2 ( ortholog_one2one ) Rat_ Olr59 ( ortholog_one2one ) Rabbit_ OR51E2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | OR52I2, OR52R1, OR52W1, OR52M1, OR52I1, OR52L1, OR52J3, OR52D1, OR52E5, OR52E2, OR52E6, OR52B4, OR52B6, OR52E1, OR52B2, OR52E4, OR52E8, OR52N4, OR52P1, OR52N5, OR52K2, OR52N1, OR52K1, OR52A1, OR52N2, OR52A5, OR56B2P, OR52H1, OR56B1, OR56B4, OR51G1, OR51B2, OR51B6, OR51G2, OR51B5, OR51B4, OR51M1, OR51Q1, OR51V1, OR51L1, OR51I1, OR51I2, OR51A2, OR51C1P, OR51A4, OR51S1, OR51F2, OR51T1, OR51A7, OR51D1, OR51E1 |
| Tissue | prostate |
| Tissue Specificity | Highly expressed in the prostate (PubMed:11707321). Also expressed in spleen, liver, olfactory epithelium, retinal pigment epithelium and medulla oblongata (PubMed:29249973, PubMed:11707321, PubMed:16491480). In the retinal pigment epithelium expression is restricted to the pigment cells and choroid (at protein level) (PubMed:29249973). Expressed in epidermal melanocytes (at protein level) (PubMed:27226631). {ECO:0000269|PubMed:11707321, ECO:0000269|PubMed:16491480, ECO:0000269|PubMed:27226631, ECO:0000269|PubMed:29249973}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:23401498, ECO:0000269|PubMed:27226631, ECO:0000269|PubMed:29249973}; Multi-pass membrane protein {ECO:0000255}. Early endosome membrane {ECO:0000269|PubMed:27226631}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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