| Gene Information | |
|---|---|
| Gene Name | OFOXD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 394 |
| Protein Names | RNA demethylase ALKBH5 (EC 1.14.11.53) (Alkylated DNA repair protein alkB homolog 5) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6P6C2 |
| Gene Card | ALKBH5 |
| Uniprot ID | Q6P6C2 |
| Pfam | PF13532 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest expression in lung, followed by testis, pancreas, spleen and ovary. {ECO:0000269|PubMed:17979886}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.2(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4NJ4 (X-ray 2.02A ) 4NRM (X-ray 2.17A ) 4NRO (X-ray 2.30A ) 4NRP (X-ray 1.80A ) 4NRQ (X-ray 2.50A ) 4O61 (X-ray 1.90A ) 4O7X (X-ray 1.78A ) 4OCT (X-ray 2.28A ) 7V4G (X-ray 2.10A ) 7WKV (X-ray 2.10A ) 7WL0 (X-ray 2.50A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus speckle {ECO:0000269|PubMed:21264265, ECO:0000269|PubMed:23177736}. |
| Mouse PG classification | NA |
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