| Gene Information | |
|---|---|
| Gene Name | RRAS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 204 |
| Protein Names | Ras-related protein R-Ras2 (EC 3.6.5.-) (Ras-like protein TC21) (Teratocarcinoma oncogene) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000133818 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P62070 |
| Gene Card | RRAS2 |
| Uniprot ID | P62070 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | no (-0.316107368) |
| Ortholog in Animals | Alpaca_ RRAS2 ( ortholog_one2one ) Dog_ RRAS2 ( ortholog_one2one ) GuineaPig_ RRAS2 ( ortholog_one2one ) Macaque_ RRAS2 ( ortholog_one2one ) Mouse_ Rras2 ( ortholog_one2one ) Rat_ Rras2 ( ortholog_one2one ) Rabbit_ RRAS2 ( ortholog_one2one ) |
| Ohnologs | RRAS, KRAS, NRAS |
| Paralogs | RRAS, RHEB, KRAS, DIRAS1, RAP2B, HRAS, RERG, RASL12, RRAD, RIT1, DIRAS2, ERAS, NKIRAS1, RALB, RASD2, GEM, DIRAS3, MRAS, RAP2A, RASD1, REM1, NKIRAS2, RALA, RAP1A, RASL11B, RAP1B, RASL10A, RASL11A, REM2, RERGL, RIT2, RHEBL1, NRAS, RAP2C, RASL10B |
| Tissue | NA |
| Tissue Specificity | Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas. {ECO:0000269|PubMed:8052619}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2ERY (X-ray 1.70A ) |
| DBSNP | rs1591495779 rs782457908 rs113954997 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:28406396, ECO:0000269|PubMed:31130282}; Lipid-anchor {ECO:0000269|PubMed:15308774, ECO:0000269|PubMed:28406396}; Cytoplasmic side. Golgi apparatus membrane {ECO:0000269|PubMed:31130282}; Lipid-anchor {ECO:0000269|PubMed:15308774}. |
| Mouse PG classification | NA |
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