| Gene Information | |
|---|---|
| Gene Name | EPN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 641 |
| Protein Names | Epsin-2 (EPS-15-interacting protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000072134 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O95208 |
| Gene Card | EPN2 |
| Uniprot ID | O95208 |
| Pfam | PF01417 |
| In ASD | no |
| Allosteric Prediction | no (-0.086086986) |
| Ortholog in Animals | Alpaca_ EPN2 ( ortholog_one2one ) Dog_ EPN2 ( ortholog_one2one ) GuineaPig_ EPN2 ( ortholog_one2one ) Macaque_ EPN2 ( ortholog_one2one ) Mouse_ Epn2 ( ortholog_one2one ) Pig_ EPN2 ( ortholog_one2one ) Rat_ Epn2 ( ortholog_one2one ) Rabbit_ EPN2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ENTHD1, MYCBPAP, CLINT1, EPN3, EPN1 |
| Tissue | NA |
| Tissue Specificity | Highest expression is found in brain. Detected at lower levels in lung and liver. {ECO:0000269|PubMed:10567358}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6587220 rs1062727 rs1062727 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10567358}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000269|PubMed:10567358}. Note=In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex. |
| Mouse PG classification | NA |
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