| Gene Information | |
|---|---|
| Gene Name | PMF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 205 |
| Protein Names | Polyamine-modulated factor 1 (PMF-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000160783 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q6P1K2 |
| Gene Card | PMF1 |
| Uniprot ID | Q6P1K2 |
| Pfam | PF03980 |
| In ASD | no |
| Allosteric Prediction | no (-0.511795745) |
| Ortholog in Animals | Alpaca_ PMF1 ( ortholog_one2one ) GuineaPig_ PMF1 ( ortholog_one2one ) Mouse_ Pmf1 ( ortholog_one2one ) Rat_ Pmf1 ( ortholog_one2one ) Rabbit_ PMF1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver. {ECO:0000269|PubMed:10419538}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001615(Rat);0.023529(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5LSJ (X-ray 3.25A ) 5LSK (X-ray 3.50A ) |
| DBSNP | rs1052053 rs1052067 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16585270}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:16585270}. Note=Associated with the kinetochore. |
| Mouse PG classification | NA |
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