| Gene Information | |
|---|---|
| Gene Name | IER5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 327 |
| Protein Names | Immediate early response gene 5 protein |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000162783 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q5VY09 |
| Gene Card | IER5 |
| Uniprot ID | Q5VY09 |
| Pfam | PF05760 |
| In ASD | no |
| Allosteric Prediction | no (-0.670483237) |
| Ortholog in Animals | Alpaca_ IER5 ( ortholog_one2one ) Macaque_ IER5 ( ortholog_one2one ) Mouse_ Ier5 ( ortholog_one2one ) Pig_ IER5 ( ortholog_one2one ) Rat_ Ier5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IER2, IER5L |
| Tissue | NA |
| Tissue Specificity | Expressed in acute myeloid leukemia (AML) cells. {ECO:0000269|PubMed:22132193}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3747955 rs3747954 rs1416829 rs1361365 rs3747951 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:25816751}. Cytoplasm {ECO:0000269|PubMed:25816751}. Note=Predominantly cytoplasmic (PubMed:25816751). Translocated in the nucleus during heat shock (PubMed:25816751). {ECO:0000269|PubMed:25816751}. |
| Mouse PG classification | NA |
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