| Gene Information | |
|---|---|
| Gene Name | PRSS12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 875 |
| Protein Names | Neurotrypsin (EC 3.4.21.-) (Leydin) (Motopsin) (Serine protease 12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000164099 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P56730 |
| Gene Card | PRSS12 |
| Uniprot ID | P56730 |
| Pfam | PF00051; PF00530; PF00089 |
| In ASD | no |
| Allosteric Prediction | no (-0.441658487) |
| Ortholog in Animals | Alpaca_ PRSS12 ( ortholog_one2one ) Alpaca_ PRSS12 ( ortholog_one2many ) Dog_ PRSS12 ( ortholog_one2one ) GuineaPig_ PRSS12 ( ortholog_one2one ) Macaque_ PRSS12 ( ortholog_one2one ) Mouse_ Prss12 ( ortholog_one2one ) Pig_ PRSS12 ( ortholog_one2one ) Rat_ Prss12 ( ortholog_one2one ) Rabbit_ PRSS12 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CD6, LOX, SSC4D, SSC5D, LGALS3BP, LOXL4, SCART1, CD163, DMBT1, LOXL3, CD5, LOXL1, CD5L, LOXL2, CD163L1 |
| Tissue | NA |
| Tissue Specificity | Brain and Leydig cells of the testis. |
| Pharmacological Animal Models | 0.087880(Chimpanzee);NULL(Mouse);0.005990(Rat);0.028571(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs28661939 rs17594503 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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